Steroid Use & Spine Red Flags

When to use, when to avoid, and urgent neurologic signs that need rapid action.

Clinician memo Systemic / Injection

Systemic Steroids

Common indications

  • Autoimmune flare (e.g., RA, PMR), severe asthma/COPD exacerbation.
  • Short course for acute radiculopathy is controversial; if used, limit duration and dose.

Avoid / caution

  • Active infection (esp. TB, fungal), uncontrolled diabetes, severe osteoporosis, peptic ulcer with GI bleed history.
  • Consider PPI, glucose monitoring, bone protection when prolonged.

Example short taper

Prednisone 40 mg daily x3–5 days → 30 mg x3d → 20 mg x3d → 10 mg x3d → stop (tailor to case).

Epidural / Injection

  • Indicated for radicular pain with imaging concordance; avoid if progressive deficit or infection.
  • Do not repeat frequently; typical interval > 2–3 months, limit total per year.
  • Check diabetes control; warn about transient glucose spikes.

Absolute contraindications: coagulopathy without correction, local/systemic infection, patient refusal.

Neurologic Emergencies

  • Cauda equina signs: bowel/bladder change, saddle anesthesia, rapidly progressive weakness.
  • Acute cord compression: bilateral weakness, spasticity, sensory level.
  • Spinal epidural abscess: fever + back pain + neuro deficit; MRI and urgent consult.

Action: urgent MRI, surgical/ED referral; do not mask with steroids unless directed by specialist.

Bone & Metabolic Protection

  • Calcium/Vit D, consider bisphosphonate if long-term systemic steroids (≥2.5–5 mg pred eq for ≥3 months).
  • Monitor BP, glucose, weight; vaccinate (influenza, pneumococcal) as appropriate.
  • Screen for TB/hepatitis risk before biologics or prolonged immunosuppression.

Patient Counseling

  • Use lowest effective dose, shortest duration; do not stop abruptly after long use.
  • Report fever, vision changes, severe mood change, black stools, or new neurologic symptoms.
  • For injections: temporary numbness/weakness may occur; seek care if symptoms worsen or fever develops.